Packaged antimicrobial medical device and preparation method thereof

Patent Name Packaging Antimicrobial Medical Devices and Methods of Making Patent Applicant Ixikon Inc. Principal Applicant United States New Jersey Inventor H. Scarazo; J.A. Fisher; J.R. Medivitt; S Luffenberg; R. Sewing Application (Patent) No. 03825554.5 Date of Application 2003.09.25 Certification Date Approval Notice No. 1713853 Auditing Notice Date 2005.12.28 Manual CD-ROM D0552 Main Classification Number A61B17/00 Classification Number A61B17/00; A61B17/04; A61B17/06; A61K31/665; A61K31/075 Division Original Application No. 2001.04 US 60/416,114; 2003.2.15 US 10/367,497; 2003.2.15 US 10/367,565 Abstract A microbiological suturing device comprising a container chamber having one or more surfaces on which are disposed antimicrobial agents selected from the group consisting of halogenated hydroxy ethers, acyloxydiphenyl ethers, and combinations thereof. An amount of antimicrobial agent sufficient to substantially inhibit bacterial colonization on the container chamber; and a suture placed in the container chamber, the suture comprising one or more surfaces on which an antimicrobial agent is disposed, the resistance micro- The agent is selected from the group consisting of halogenated hydroxy ethers, acyloxy diphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonies on the suture; methods of making antimicrobial suture devices; and have antimicrobial properties A braided suture comprising an elongated braided structure formed from a plurality of polymeric filaments, the filament formed from a polymeric material that can be absorbed under physiological conditions, and a coating material disposed on the elongated braided structure The coating includes an absorbable polymer that forms a film, a substantially water-insoluble fatty acid salt, and an effective amount of a fatty acid selected from the group consisting of halohydroxyethers, halooxy-diphenyl ethers, and acyloxydiphenyls. The ether and its combined antimicrobial agent, when the suture is implanted in a patient, is effective to substantially inhibit the growth of microorganisms on or near the suture. Sovereignty item 1. An antimicrobial suturing device comprising a container chamber containing one or more surfaces on which an antimicrobial agent is disposed and said antimicrobial agent is selected from the group consisting of halogenated hydroxy ethers and acyloxy diamines. Phenyl ether and combinations thereof in an amount sufficient to substantially inhibit bacterial colonization on the chamber of the container; and a suture placed within the container chamber, the suture comprising one or more surfaces, disposed on the surface An antimicrobial agent is selected from the group consisting of halohydroxyethers, acyloxydiphenylethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonies on the suture. International Application 2003-09-25 PCT/US2003/030600 International Publication 2004-04-22 WO2004/032704 Date of Entry into the Country Patent Agencies China Patent Agency (Hong Kong) Co., Ltd. Agency Address Agent Honghong Yan Duanling