Research Reagents-Germany develops new drug for treatment of sepsis

Its affiliated Medical and Biological Center has developed a new drug for the treatment of sepsis, which can effectively inhibit the inflammation caused by lipopolysaccharide when sepsis occurs.

The Leibniz Association issued a communiqué that day, the key to treating sepsis is the substance called lipopolysaccharide. When sepsis occurs, the concentration of lipopolysaccharide in the patient's body will be greatly increased, so that the body will have a catastrophic inflammatory response. So far, antibiotics and other drugs used to treat sepsis cannot effectively control the concentration of lipopolysaccharide.

Researchers using 20 to 50 amino acids to synthesize antimicrobial peptides can be combined with lipopolysaccharide, thereby achieving the purpose of reducing the concentration of lipopolysaccharide in patients with sepsis. Studies have shown that when the concentration ratio of this synthetic peptide to lipopolysaccharide is 10 to 1, the inflammation can be effectively suppressed.

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